Scientist - ADC DMPK Aurigene Oncology Limited

About Aurigene Oncology Limited

Job Description

Desired Profile: M. Pharm (Pharmacology / Pharmaceutical Analysis) / M.Sc. (Biochemistry / Pharmaceutical Chemistry) with 11-14 years or Ph.D. with 2-5 years experience in large molecule/ADC PK and bioanalysis, Antibody Drug Conjugate characterisation and bioanalysis, mass spectrometry-HRMS, Q-TOF & Triple quad Roles & Responsibilities: Expert in designing and executing DMPK studies to support antibody-drug conjugate (ADC) and monoclonal antibody (mAb) programs, from discovery through IND-enabling stages. Extensive experience in quantification of biologics including antibodies, therapeutic proteins, ADCs, and peptides using LC-MS/MS, MSD, and ELISA platforms. Proficient in advanced bioinformatics tools such as BioPharma Finder, MaxQuant, Spectronaut, and other relevant analytical software. Skilled in applying innovative techniques for function-based identification and selection of ADC and mAb lead candidates, with a strong focus on DMPK profiling to ensure safe and effective therapeutic development. Experienced in interpreting complex DMPK data and providing actionable insights to cross-functional project teams. Actively represent DMPK functions in internal and external meetings, fostering collaboration and strategic alignment. Collaborate closely with cross-functional departments to address ADC-related challenges and deliver integrated solutions from target validation to IND submission. Accountable for authoring and reviewing SOPs, study protocols, reports, and regulatory documentation to support both GLP and non-GLP studies. Strong foundational knowledge of DMPK principles, including PK/PD, toxicology, and translational sciences. Demonstrated capabilities in communication, innovation, and team leadership.,